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10. Risk of Carcinogenesis on Radiation Therapy for Keloids
Rei Ogawa1, Sumiko Yoshitatsu2, Tsuguhiro
Miyashita3, Ken Yoshida4
1:Deaprtment of Plastic, Reconstructive and Aesthetic Surgery, Nippon
Medical School, Tokyo, Japan
2:Department of Plastic Surgery, Osaka National Hospital, Osaka, Japan
3:Department of Radiology, Nippon Medical School, Tokyo, Japan
4:Department of Radiology, Osaka National Hospital, Osaka, Japan
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An important concern associated with radiation therapy is the risk of
inducing malignant tumors. Thus, we studied previous papers on malignant
tumors associated with radiation therapy for keloids. Five papers were
examined, however, whether appropriate dose of radiation and appropriate
protection of surrounding tissues including mammary gland and thyroid
were used for these cases is unclear. With regard to the indication of
radiation therapy for keloids, there is a questionnaire study on
radiation oncologists in 508 facilities worldwide. In the results, 78%
of the facilities responded that radiation therapy is an accepted
indication. With regard to USA and Canada, over 90% of 77 facilities
accepted radiation therapy for keloids. Generally, surgeons tend to
avoid radiation therapy for benign tumors including keloids for fear of
inducing a malignant tumor, but it is suggested that surgeons should
have a closer discussion with a radiation oncologist and consider
radiation therapy as a treatment choice for keloid. |
