5. Retrospective analysis of postoperative electron-beam
irradiation therapy for keloids
Tosa M1, Yamamoto A2, Sato M2,
Murakami M1, Hyakusoku H3
1: Department of Plastic and Reconstructive Surgery, Nippon
Medical School2nd Hosupital, Kanagawa, Japan
2: Department of Radiation, Nippon Medical School 2nd Hospital,
Kawasaki, Japan
3: Department of Plastic and Reconstructive Surgery, Nippon
Medical School Hospital, Tokyo, Japan
The authors report the outcomes of 186 patients with 241 keloids treated
with a protocol of extralesional excision and postoperative
electron-beam irradiation therapy. The design of the study was a
retrosoective analysis of up to 2-year follow-up data. The total dose of
irradiation delivered was 15-Gy in 3 days, with a daily fraction of 5-Gy
of electron beam irradiation given within 24 hours of the operation.
Recurrence occurred at 12 sites on 69 anterior chest walls (17.4%), 3
sites on 18 scapular regions (16.7%), 1 site on 5 upper limbs (20.0%),
and 1 site on 8 lower limbs (12.0%). The ear lobe showed no greater
chance of recurrence than the other sites of the body. The overall
recurrence rate was 10.8%. Postoperative electron-beam irradiation
therapy for keloids is effective in preventing a recurrence at excision
sites.
