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Papers of The 2nd Japan Scar Workshop |
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15. Histological characteristics of scars, hypertrophic scars, and
keloids
Miki Izumi,
Department of Diagnostic Pathology, Tokyo Medical University, Tokyo,
Japan
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In general, scars form at sites of injury as a result of proliferation
of thick collagen fibers. Hypertrophic scars and keloids proliferate
beyond the range of the injury and create well-demarcated nodular
lesions. Hypertrophic scars show characteristic parallel, nodular, or
whirl structures. In keloids, pathognomonic keloid fibers are
characterized by broad acidic bands of collagen proliferating
haphazardly. The pathological differences between the etiologies
(pierced keloid, acne keloidalis, etc), inter/intra lesion sites, and
chronology should be further investigated. |
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